San Francisco 49ers top scorers look to capitalize on opportunities early against Detroit Lions stout defense.

Less than a year ago, the 49ers and the Lions were the two best teams in the NFC. Now the Lions are on the verge of locking up the no. 1 seed.

The playoff-eliminated San Francisco 49ers are set to host the Detroit Lions on Monday night in a rematch of last season's ...

The San Francisco 49ers face slim odds of landing a top-nine pick in the 2025 NFL Draft. The Carolina Panthers and New York ...

The 2024 Detroit Lions have their sights set on clinching the No. 1 seed in the NFC (a win over the 49ers and a Vikings loss ...

Best streaming services for Lions vs. 49ers. Detroit Lions vs. San Francisco 49ers will be aired locally in the Bay Area. It ...

The Lions announced that they are signing LB Kwon Alexander to the practice squad and signed DB Morice Norris to the active ...

After one of the most decorated playing careers in both college and NFL history for any defensive back, Ed Reed has dabbled ...

Detroit Lions offensive coordinator Ben Johnson is reportedly 'intrigued' by one head coach opening this offseason.

Dolphins quarterback Tua Tagovailoa is unlikely to play on Sunday against the Browns. Tagovailoa has been downgraded to doubtful on the injury report. Tagovailoa was initially listed as questionable ...

The Detroit Lions and San Francisco 49ers met 11 months ago at Levi's Stadium with a trip to the Super Bowl on the line. San Francisco used a furious second half comeback to steal the NFC Championship ...

Only once before have the stakes been greater at the Rose Bowl for the No. 1 Ducks than they will be on Wednesday against ...