Gizmodo Science Fair: The First RNA Recovered From an Extinct Animal
A team of paleogeneticists is a winner of the 2024 Gizmodo Science Fair for recovering RNA from a museum specimen of a ...
EurekAlert!1d
HiTIP-seq profiles epigenomic reprogramming of patient-derived diffuse midline glioma stem cells to epigenetic therapy (IMAGE)
H3K27-altered, is a lethal pediatric high-grade tumor, lacking effective treatment options, primarily depending on clinical trials. Epigenetic agent-based immunotherapy has shown promise, but the ...
eLife1d
Differential growth and transcriptomic profile of stem cell-derived midbrain astrocytes
Using deep single cell RNA sequencing, we identified distinct transcriptomic signatures of midbrain floor plate-derived astrocytes. Our study highlights the need for rigorous characterisation of ...
eLife2d
Chromatin endogenous cleavage provides a global view of RNA polymerase II transcription kinetics
However, ChIP-seq and ChEC-seq2 reveal strikingly diUerent patterns of enrichment of yeast RNA polymerase II. We hypothesized that this reflects distinct populations of RNAPII, some of which are ...