a protein domain common to all adhesion GPCRs. It should help to elucidate the role of this protein domain in disease and pave the way for more precise experimental approaches. The research has ...

Using the CRISPR/Cas9 genome-editing system to mutate the gene regions encoding particular protein domains could result in a new and more efficient method to screen for druggable protein targets ...

We will therefore focus on the role of protein phosphatases in the control ... Figure 4: The phosphorylation state of the C-terminal domain of RNA polymerase II controls transcript maturation.

A transformative study has uncovered the pivotal role of the protein Naked cuticle homolog 2 (NKD2) in regulating the differentiation of bone-forming osteoblasts and bone-resorbing osteoclasts.

A research team at the University of Cologne has made a significant breakthrough in understanding the role of the tau protein in Alzheimer's disease. Using human induced pluripotent stem cells ...

Amyloid precursor protein (APP) plays a central role in Alzheimer ... crystal structure of the N-terminal, heparin-binding domain of APP (residues 28–123), which is responsible, among other ...