For example, TP53, which encodes multiple proteins, is the most commonly mutated gene in cancers. To address this, Fajac et al. used genome editing to make mouse strains that were still able to ...

Genetic variability and sex-specific differences may play a role in sickle cell disease (SCD)-related pain; however, more ...

Disrupted cholesterol homeostasis plays a critical role in the development of multiple diseases, such as cardiovascular disease and cancer. However, the role of cholesterol in inflammatory bowel ...

Genomic sequencing of nearly all living kākāpō reveals its variations in plumage color evolved to avoid the sharp eyes of ...

“This effort is a culmination of many years of dreaming about such an opportunity and finally getting access to the data and funding to make it happen,” said James E. Koltes, associate professor of ...

Study reveals nine gene variants linked to ovarian aging and cancer risk, with implications for reproductive longevity and de ...

Inc., a direct-to-consumer genetics company. The team focused on three specific single-nucleotide polymorphisms (SNPs) known to influence alcohol consumption. Abraham A. Palmer, Ph.D., professor and ...

The developed statistical method paves the way for next generation demographic and selection inference by combining information from several heritable genomic and epigenomic markers.

The kākāpō individual Hoki as an example of the green feather color polymorphism. Aotearoa New Zealand’s flightless parrot, ...

New research highlights how the kākāpō, a unique flightless bird from New Zealand, evolved green and olive color variations ...

Retinoblastoma is a rare, aggressive genetic childhood cancer that results from a mutation that inactivates the RB1 gene, the ...

The variant between homologous chromosomes significantly influences biological phenotypes and play an important role in gene expression and function. Haplotype refers to the combination of correlated ...