Purpose. The effects of genetic polymorphisms on the pharmacokinetics of calcineurin inhibitors were examined. Pharmacogenetics examines the relationship between single-gene polymorphisms and the ...

Precisely how lowered levels of the gene product, an enzyme called hexoseaminidase A, protect against TB isn't known. Balanced polymorphism may explain why cystic fibrosis is so common- the ...

Balancing selection, in contrast to directional selection, maintains genetic polymorphism in populations. For example, if heterozygotes at a locus have higher fitness than homozygotes (a scenario ...

In Figure 1, scientists used rep-PCR (a form of genomic fingerprinting that involves primers specific to naturally occurring repetitive sequences) to look for genetic polymorphisms in the clinical ...

Study reveals nine gene variants linked to ovarian aging and cancer risk, with implications for reproductive longevity and de ...

DNA-based diets leverage genetic insights to customize nutrition, optimize health, and offer personalized dietary ...

Analyses of the Glu298Asp polymorphism in exon 7 and VNTR polymorphism in intron 4 of the eNOS gene were made by the polymerase chain reaction (PCR)-restriction fragment length polymorphism technique ...

Genetic variability and sex-specific differences may play a role in sickle cell disease (SCD)-related pain; however, more ...

Objective To investigate the potential association of angiotensin converting enzyme (ACE) gene polymorphism (rs4340 and rs4343) with atrial fibrillation. Methods A total of 205 patients were recruited ...

We hypothesised that hepatitis C virus (HCV) infected subjects with progressive fibrosis, classified using strict criteria based on histology at biopsy in addition to disease duration would be more ...

aFrench National Institute of Health and Medical Research (INSERM) U 557, University of Paris 13, Bobigny, France bFrench National Institute for Agronomical Research (INRA) U 1125, University of Paris ...

2006;63(23):2340-2348. MDR1 (ABCB1) T-129C, C1236T, G2677(T,A), C3435T No difference observed for cyclosporine and any CYP3A5 polymorphism Wild-type carriers of MDR1 (ABCB1) 1236 had lower dose ...