Neuroscientists can now make precise genetic tweaks to the neurons that are most affected by brain diseases such as Parkinson ...

The assumption that underlies this is that a mouse or monkey brain serves as ... such as the amygdala and the entorhinal cortex. Recently, Mormann and his team identified smell-specific concept ...

The entorhinal cortex is hit by tangles first—in Braak stages I-II ... she noted. Previous studies in mouse models suggest that loss of reelin renders synapses extremely sensitive to even low levels ...

2019). Instead, Zhao et al. show that, in their mouse model, cell deterioration and death in the entorhinal cortex are driven by silencing of specific neuronal activity. Zhao et al. also demonstrate ...

The proposed network recalls the reward location by tracing them in its mind in order. We simulated a virtual mouse that explores a figure-eight maze and recalls the route to the reward location.

Here, we utilized trace fear conditioning to study the formation of trace fear memory in mice. We identified the entorhinal cortex (EC) as a critical component of sensory signaling to the amygdala. We ...

There is a critical need for new and better animal models for Alzheimer’s disease that can stand between mouse models and human clinical ... in a brain region called the entorhinal cortex, which is ...

Remarkably, the synchronization of neuronal activity in the hippocampus required an intact connection with the medial entorhinal cortex (MEC). In line with this observation, we detected an increase in ...

The mouse learns to run down a hallway to a door ... "Perhaps this is because they are losing some of the basic functions of the entorhinal cortex, which is one of the first brain regions affected ...

Center for NeuroScience, Swammerdam Institute for Life Sciences, University of Amsterdam, Amsterdam, Netherlands The perirhinal (PER) and entorhinal cortex (EC ... imaging in horizontal mouse brain ...