Jamie-Lynn Sigler and Robert Iler, who played siblings Meadow and A.J. Soprano, respectively, face off in PEOPLE's exclusive ...

Christina Applegate and Jamie-Lynn Sigler share painful MS experiences on MesSy podcast, offering support and advice for ...

Jamie-Lynn Sigler is going up against her Sopranos brother, Robert Iler, on The $100,000 Pyramid! In PEOPLE's exclusive look at the March 23 episode of the game show, the two former costars ...

Ed O’Neill turned heads during a surprise appearance on his daughter Claire’s TikTok. The video – which was posted Monday, ...

Christina Applegate is letting fans in on some of the details of her struggle against MS over the past three years.

The actress says the autoimmune disease has caused major digestive issues affecting her gastrointestinal system and resulting ...

Christina Applegate shared a health update on her multiple sclerosis battle, revealing she's been hospitalized over 30 times ...

Selma Blair looked sensational amid her MS battle as she posed with Melanie Griffith at a book launch in LA on Tuesday night.

Friends and Anchorman actress Christina Applegate is one of several famous faces to be living with MS, a condition that is ...

Christina Applegate has been diagnosed with multiple sclerosis (MS) and has been receiving treatment for the condition since ...

Pawn Stars personality Rick Harrison is reflecting on the death of his son, Adam, at the age of 39. Adam died from a fentanyl ...