RNA sequencing (RNA-seq) is a powerful tool for molecular biologists ... 2 Scientists are designing FFPE sample-tailored RNA library preparation protocols, reagents, and kits to remove this bottleneck ...

Single-cell analysis offers a unique perspective of the genetic and molecular features of individual cells. In this article, ...

The authors present a valuable study exploring the interaction between JNK signaling and high sucrose feeding. The strength of evidence supporting these observations is solid, including multi-tissue ...

By exploring single cell RNA-sequencing data from clinical trials using CRISPR-Cas9 engineered T cells, the researchers found that a clinical trial using a different protocol, where scientists edited ...

Here, we show that the timing of blastomere polarization at the 8-cell stage is asynchronous, and that the heterogeneity between the blastomeres at the 4-cell stage influences cell fate specification ...

Using single-cell RNA sequencing of mouse colonic sensory neurons ... We performed deep scRNAseq using a modified Smart-seq2 protocol on 399 colonic sensory neurons innervating the mouse colon ...

The number of California dairy herds reported to have outbreaks of H5N1 bird flu has grown to eight.

Single-cell RNA sequencing (scRNA-seq ... This has been dealt with in many scRNA-seq protocols by the integration of unique molecular identifiers (UMIs) which tag sequence reads originating from an ...

Count-based differential expression analysis of RNA sequencing data using R and Bioconductor Simon Anders1, Davis J McCarthy2,3, Yunshun Chen4,5, Michal Okoniewski6, Gordon K Smyth4,7, Wolfgang Huber1 ...

New research published in The Journal of Neuroscience demonstrates that the cognitive benefits of physical exercise can be ...