Mapping a human cell gives researchers a view of subcellular architecture and sheds light on how cancer develops.

Senescence, aging, and age-related diseases represent complex biological phenomena with significant impacts on human health, ...

In biology classes from high school through university, I learned that mitochondria are little objects that reside within each cell and serve as “powerhouses,” combining oxygen and food to ...

In biology classes from high school through university, I learned that mitochondria are little objects that reside within each cell and serve as “powerhouses,” combining oxygen and food to ...

A schematic of a cardiomyocyte to highlight the location of subsarcolemmal (SSM ... Based Signaling in Response to ROS Production Mitochondria serve as important signaling nodes for cell survival and ...

The biochemical characterization of CDM in cells also yielded insight into the mechanism ... In order to investigate this further, we next imaged more carefully mitochondria and CDM location, as ...

The mutated stem cells also contained turbocharged mitochondria, which gave the cells a strong competitive growth advantage. "This was really unexpected," Trowbridge said. "This gene was not ...

4A). To further characterize Mpf1, we aimed to determine its subcellular location. WT cells expressing Mpf1-3HA were fractionated into whole cell lysate (WCL), ER, cytosol and mitochondria and these ...

Instead, their structure and function vary depending on their location within the neuron ... Institute’s Center for Neurobiology Research. Neuronal mitochondria are diverse across cell types and ...

The energy needed to appropriately function is limited based on the cell’s mitochondria – an organelle responsible for generating energy for cell activity. As a result, the lack of T cell antitumor ...

mitochondria are rather dynamic. They constantly shift in size, number and location, traveling between many different parts of the cells to meet different demands. These mitochondrial dynamics are ...