The researchers identified the structure of this machine, the mitochondrial pyruvate carrier (MPC), and 50 years since its discovery, have shown how it operates like the lock on a canal to transport ...

Professor Kunji said: "Drugs inhibiting the function of the carrier can remodel how mitochondria work ... This creates new ...

Researchers at the University of Cologne found that mitochondrial dysfunction leads to early skeletal aging by disrupting ...

After more than five decades of mystery, scientists have finally unveiled the detailed structure and function of a ...

A medical breakthrough could result in the first treatment for rare but serious diseases in which genetic defects disrupt ...

Stealth BioTherapeutics Inc. (the "Company" or "Stealth"), a clinical-stage biotechnology company focused on the discovery, development and commercialization of novel therapies for diseases involving ...

Without it, the mitochondria cannot function normally and ... has analyzed the molecule's structure, including by means of cryo-electron microscopy. "We demonstrate exactly where the molecule ...

Fifty years since its discovery, scientists have finally worked out how a molecular machine found in mitochondria, the 'powerhouses' of our cells, allows us to make the fuel we need from sugars, a ...

But which part of the mitochondria’s structure or function protected the cells remains unknown, says Hayakawa. Lung cells might also benefit from a mitochondrial boost during a crisis ...

Without it, the mitochondria cannot function normally and ... has analyzed the molecule's structure, including by means of cryo-electron microscopy. "We demonstrate exactly where the molecule ...

The mitochondrial protein that controls calcium transport could be a promising target for Alzheimer's and heart disease drugs ...