(A–H) Western blots and quantitative PCR were performed to analyze IRF8 levels in the livers of C57BL/6J male mice fed with HFD or CD (A, B) (n = 5 biologically independent mice), lean or ob/ob ...

But since it’s processed through the liver, it may increase your risk of NAFLD (now called MASLD). Metabolic dysfunction-associated steatotic liver disease (MASLD), formerly called nonalcoholic ...

Liver diseases are any diseases that affect the functioning of the liver. Liver diseases can be inherited (such as Wilson disease and alpha 1-antitrypsin deficiency) or acquired (for example ...

Non-alcoholic fatty liver disease (NAFLD) is a hepatic metabolic syndrome resulting from lipid metabolic imbalance. Interferon regulatory factor 8 (IRF8) is well known for its roles in immune cell ...

Conclusion: In conclusion, circ_0098181 exerts a significant anti-fibrotic effect by binding PKM2 to repress its nuclear translocation and inhibiting hepatic inflammation, suggesting the promising ...