Purpose. The effects of genetic polymorphisms on the pharmacokinetics of calcineurin inhibitors were examined. Pharmacogenetics examines the relationship between single-gene polymorphisms and the ...

The crucian carp (Carassius auratus) is a common freshwater fish species in China, and its aquaculture mainly depends on ...

Balancing selection, in contrast to directional selection, maintains genetic polymorphism in populations. For example, if heterozygotes at a locus have higher fitness than homozygotes (a scenario ...

Precisely how lowered levels of the gene product, an enzyme called hexoseaminidase A, protect against TB isn't known. Balanced polymorphism may explain why cystic fibrosis is so common- the ...

The situation is further complicated by polymorphisms in the PAI-1 gene, particularly the 4G/5G polymorphism in its promoter ...

Snap bean (Phaseolus vulgaris L.) is a significant vegetable crop globally, with its immature pods harvested as the edible ...

Variations in a DNA building block of genes tied to processes like inflammation associated in a study with disease type, ...

Salivary DNA was collected using a DNA Genotek kit (ON, Canada), and TaqMan assays analyzed COL5A1 rs12722 C/T and rs10628678 AGGG/- (deletion) polymorphisms. Risk Assessment and Main Outcomes We ...

Researchers investigated the population characteristics of two hybrid crucian carp strains based on one nuclear gene ...

2006;63(23):2340-2348. MDR1 (ABCB1) T-129C, C1236T, G2677(T,A), C3435T No difference observed for cyclosporine and any CYP3A5 polymorphism Wild-type carriers of MDR1 (ABCB1) 1236 had lower dose ...