"We created a new mouse model in which we showed that spatial memory decays when the entorhinal cortex is not functioning properly," said co-corresponding author Dr. Joanna Jankowsky, associate ...

The mouse learns to run down a hallway to a door ... "Perhaps this is because they are losing some of the basic functions of the entorhinal cortex, which is one of the first brain regions affected ...

The retromer subunit VPS26b seems crucial for neurons. Mouse VPS26b knockouts had more Aβ, less entorhinal cortex neurotransmission, and worse memory function. Transentorhinal cortex from AD cases was ...

The study, led by Dr. Jeffrey Magee, professor of neuroscience at Baylor, investigator with Howard Hughes Medical Institute and the Duncan NRI, reveals how the entorhinal cortex (EC) sends instructive ...

But a study published today in Science finds that a brain region called entorhinal cortex plays a new and independent role in memory. A team of researchers led by Jozsef Csicsvari, Professor at ...

In rodents, electrical stimulation of the perforant pathway, which originates in the entorhinal cortex and projects into the hippocampus, results in long-term potentiation, release of ...

The signals are thought to travel from here to regions of the brain such as the amygdala, piriform cortex, and entorhinal cortex, which are the primary olfactory cortex regions. Studies using ...

If so, you can thank your entorhinal cortex, a brain area recently identified as being responsible for our sense of direction. Variation in the signals in this area might even explain why some ...

The man was protected because another mutation in a different gene blocked the disease from entering his entorhinal cortex. That tiny area of the brain is a hub for neurons involved in memory ...