Scientists at the Centro Nacional de Investigaciones Cardiovasculares Carlos III (CNIC), in collaboration with national and ...

To address the challenge of controlling protein activation in living animals for gain-of-function studies, researchers from ...

Atherosclerosis is the buildup of fat and calcium in the walls of blood vessels and represents the most common cause of ...

CCR4 deficiency effects on the early atherosclerosis development in the Apoe-/-mice model were demonstrated by a quantitative analysis of the lesion area, inflammatory cell content and the expression ...

An antibody called bFKB1 improves liver disease and atherosclerosis in a mouse model of metabolic dysfunction-associated steatohepatitis (MASH), which is associated with obesity. The antibody also ...

APOE-null mice are a widely used, consensus model for atherosclerosis in the general population, while LDLR-null mice are the model for homozygous familial hypercholesterolemia, a genetic condition in ...

The authors have previously shown that beta carotene reduces atherosclerosis progress and hepatic lipid metabolism, and now they seek to extend these findings by feeding mice a diet with excess beta ...

Bitterroot Bio Inc. presented data on an anti-CD47 hybrid protein, BRB-002, tested in a murine model of atherosclerosis. BRB-002 was tested at 2.5 or 10 mg/kg i.p. 3x/week after a high-fat diet.

The Apoe −/− mouse model is well established for the study of human atherosclerosis. These mice are prone to atherosclerosis. The research team went on to show that TRPM2 deficiency reduces ...

In this study, P. gingivalis was used to generate an experimental periodontitis model in ApoE −/− mice. Aggravated atherosclerosis plaques, enhancement of TMAO in peripheral blood and increased FMO3, ...

The drug was given to mice lacking certain transport molecules for the blood lipid cholesterol and that thus serve as an animal model for atherosclerosis (the mice had modifications in the gene ...