An antibody called bFKB1 improves liver disease and atherosclerosis in a mouse model of metabolic dysfunction-associated steatohepatitis (MASH), which is associated with obesity. The antibody also ...

The drug was given to mice lacking certain transport molecules for the blood lipid cholesterol and that thus serve as an animal model for atherosclerosis (the mice had modifications in the gene ...

Scientists from the Cardiovascular Research Center at the University of Virginia School of Medicine and Astrazeneca plc have developed a new mouse model of cardiovascular disease associated with ...

"The use of this transparent zebrafish model is a promising method to screen for new drugs and cardiovascular imaging agents," said Miller. Atherosclerosis ... been induced in mice and rabbits ...

Bitterroot Bio Inc. presented data on an anti-CD47 hybrid protein, BRB-002, tested in a murine model of atherosclerosis. BRB-002 was tested at 2.5 or 10 mg/kg i.p. 3x/week after a high-fat diet.

ApoE-knockout mice-which develop spontaneous hypercholesterolemia and atherosclerosis after about four months ... the authors write. In this model, yet unknown disease stimuli could modulate in a ...

functional version of good cholesterol -- the HDL protein shuttle that pulls cholesterol out of cells -- reversed the progression of atherosclerosis in mice with diabetes. The results, say the ...

Mice receiving bone marrow from Tet2 knockout ... heart disease or early-onset myocardial infarction. In a murine model of atherosclerosis, the loss of Tet2 function in hematopoietic cells ...

The team examined CMA’s role in the condition by first feeding mice a high-fat diet for 12 weeks, and monitored CMA activity in two cell types that malfunction in atherosclerosis. CMA activity ...

“Moreover, no scalable 3D atherosclerosis model is available for the evaluation of potential therapeutics via high-throughput assays.” Cardiovascular disease — primarily caused by atherosclerosis — is ...