We all forget things now and then—people’s names, where you put your car keys, that dentist appointment that was scheduled before you got your new calendar. As we age, forgetfulness may worsen and begin to disrupt thinking abilities.

The number of Americans who will develop dementia—a progressive decline in memory, thinking skills, communication, and overall cognitive ability—is estimated to double by 2060, from 514,000 new cases each year in 2020 to one million cases each year by 2060, according to a study in Nature Medicine.

A new study found a higher lifetime risk than previously thought: After age 55, people have up to a 4 in 10 chance of eventually developing dementia.

A new study estimates new dementia cases to sit around one million annually by 2060, doubling current numbers.