The cells' sickle shape and associated fragility result in rapid RBC destruction by a patient's own body. This leads to leads to anemia, as well as congestion and fibrosis of the spleen at an ...

I was recently at the American Red Cross to donate blood and was given interesting material on the need for Black blood donors for sickle cell anemia patients.

Hemoglobin has played a central role in the understanding of many biochemical and biophysical principles, as Eaton and colleagues point out on page 351 of this issue of Nature Structural Biology.

Hydroxyurea remains effective long-term in reducing emergency department visits and hospital days for children living with ...