The 49ers have a record of 6-11. Who wins NFL Week 18 game? San Francisco 49ers vs Arizona Cardinals picks, predictions Watch 49ers at Cardinals with FUBO (free trial) Kyler Murray hit Marvin ...

Will the 49ers be able to march up the field at their leisure again, or will the Cardinals flip the script? San Francisco is a big 13.5-point favorite against Arizona, according to the latest NFL ...

In Dane Brugler's latest mock draft, he projects the 49ers to draft George defensive end Mykel Williams with the 11th pick. And with the 12th pick, the Cowboys take Arizona wide receiver Tetairoa ...

The Denver Broncos are signing San Francisco 49ers safety Talanoa Hufanga to a three-year deal worth up to $45 million.

Trade: 49ers are trading Jordan Mason to the Minnesota Vikings. Viking are signing Mason to a 2-year deal with over $7 ...

Making headway in the always-formidable NFC West has never been easy. Consider what has occurred in this division dating back since 2012. The San Francisco 49er ...