Tangentially, other biophysicists tried to figure out their own early version of the patch clamp method. David Clapham, now a biophysicist at the Howard Hughes Medical Institute, became fascinated ...

Since its introduction by Bert Sakmann and Erwin Neher in 1978, patch-clamping techniques have become widely accessible with commercially available equipment. And while the science of patch clamping ...

Though there is another neural recording technique — the use of patch-clamp electrodes, which won the Nobel Prize — it does not measure neuron activity in a parallel fashion. Patch-clamps only ...

Sutter Instrument is proud to introduce the latest tool for electrophysiology research, the dPatch ® Digital Patch Clamp Amplifier. Using high-speed digital processing, matched with high ...

In contrast, a patch-clamp electrode, the gold standard in neuronal recording, can effectively get inside an individual neuron to record a faint synaptic signal with high sensitivity, and thus can ...