Despite decades of research since the first sequencing of an organism in 1995, scientists still do not understand exactly how the information in genes is converted into an organism's phenotype, its ...

However, we realize now that functional genomics—how genotype translates to phenotype—is just as important. Multiomics helps us sort through the functional part of functional genomics. You might also ...

Combining CRISPR screening with single-cell RNA sequencing, Vienna-based Aelian Biotechnology has developed a new discovery tool for functional genomics. It enables biotech and pharma companies to ...

Phenotype-driven approach ... This is the reason that the mouse has been chosen as the model system for functional genomics and human diseases. To realize this goal it is necessary to promote ...

The Norman Lab aims to combine large-scale functional genomics experiments with computational modeling ... Mapping information-rich genotype-phenotype landscapes with genome-scale Perturb-seq. Cell ...

In addition to Tau transgenic flies, we will perform functional studies based on expression of the human amyloid-Beta peptide (Aß), which is similarly associated with neuronal toxicity in Drosophila.

ROME, April 3, 2025 /PRNewswire/ -- IRBM, an integrated Contract Research Organization (CRO) specializing in preclinical drug discovery, has established a comprehensive Functional Genomics ...

combined with the strengths of commercially important fishes as models for functional genomic, ecological and evolutionary research. Our aim is to link genotype, phenotype and fitness of important ...

Our team uses a comprehensive experimental approach that combines cancer models, functional genomics and the analysis of human patient data to identify tissues-specific mechanisms of cancer ...