A new pill, tavapadon, has shown potential in easing Parkinson’s symptoms while limiting side effects. In patients taking at ...

The modified LSD, which they named JRT, did just that—and more. It stimulated neurons to sprout new dendritic branches and ...

The highly selective partial agonist at D1 and D5 receptors significantly improves motor function in patients recently ...

Dopamine’s effects in the brain are mediated by postsynaptic D1 and D2 receptors. Adenosine A1 and A2A receptors are uniquely positioned to counteract the excessive stimulation of dopamine receptors ...

“The end game is trying to relate [dopamine signaling] back to schizophrenia and other disorders with working memory impairment,” study coauthor Joshua Roffman of MGH and Harvard University told The ...

“Tardive” means delayed and “dyskinesia” means abnormal involuntary movement. The problem is caused by exposure to medications that block dopamine receptors (most commonly certain antidepressant, ...

To this end, radioreceptor and functional studies of these three compounds were conducted at each of the known molecular isoforms of the dopamine receptors in several transfection systems ...

Here, the authors report a modular click ligand-directed approach to covalently attach fluorescent dyes to endogenous dopamine D1 receptors in live cells. CXCR3 and CXCR7 are chemokine receptors ...

A new study in Engineering explores the role of astrocytic G protein-coupled receptors in drug addiction. It shows that these receptors, including ...