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Its lead product candidate is SER 252 (POZ-apomorphine), a POZ conjugate for the treatment of advanced Parkinson’s disease that is in preclinical stage development; and POZ-lipids, a non ...
Ubiquitin (Ub) and ubiquitin-like protein (Ubl) conjugation occurs in sequential steps 1. Proteases first expose a conserved C-terminal di-glycine (Gly-Gly) motif of Ub or Ubl that is then ...