Iran launched multiple deadly waves of missiles and drones toward Israel into Saturday morning following Israel’s unprecedented strikes aimed at destroying Iran’s nuclear program and decapitating its military leadership.

Iran and Israel exchanged more airstrikes overnight Friday after Israel mainly attacked Iranian nuclear and military targets one day earlier. Though some missiles struck civilian populations, residents in both nations said they support their government's airstrikes.

The retaliatory strikes came on Saturday, a day after Israel killed top Iranian military leaders and scientists and destroyed an aboveground nuclear enrichment plant near Natanz.

Little more than a day after Israel launched its sudden campaign of airstrikes targeting Iran’s nuclear facilities, senior military and civilian leaders, the country's military spokesperson Effie Defrin said 70 warplanes attacked more than 40 targets in Tehran overnight,

In response to Israel’s attack, Iran fired back with more than 100 drones. NBC News’ Chief International Correspondent Keir Simmons reports more. Former NATO Supreme Allied Commander retired Gen. Wesley Clark and Senior Fellow at the Carnegie Endowment for International Peace Aaron David Miller join Ana Cabrera to examine the possibility of further attacks.

Launching weapons from within their territory forces adversaries to look not only outward but also inside for threats, one expert said.

The U.S. military is operating in the air, on land and at sea to shoot down Iranian missiles fired at Israel.

Markets are having another bout of nerves after Israel bombed Iran, which is believed to have fired back drones in response.